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Development of new antifungal agents and strategies


Development of new antifungal agents and strategies
While filamentous fungi are considered as important industrial production hosts, they also pose a severe threat to humans and the environment. An increasing number of resistant human and plant-pathogenic filamentous fungi has resulted in a demand for new antifungal agents and strategies.
Applying systems biology tools to Aspergillus niger, target molecules for antifungal strategies were identified which have resulted in, inter alia, the foundation of the spin-off company HiTeXacoat. Our aim is to identify additional target molecules and to test their interaction with microbial and herbal ingredients using high throughputapproaches. Thus, innovative and environmentally compatible and highly specific antifungal substances can be identified.
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