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Inhalt des Dokuments

Publikationen

2019

Bruno R, Maresca M, Canaan S, Cavalier JF, Mabrouk K, Boidin-Wichlacz C, Olleik H, Zeppilli D, Brodin P, Massol F, Jollivet D, Jung S, Tasiemski A. Worms' Antimicrobial Peptides. Mar Drugs (2019)17(9). DOI: 10.3390/md17090512.

Antypenko L, Sadykova Z, Shabelnyk K, Meyer F, Kovalenko S, Meyer V, Garbe LA, Steffens K. Synthesis and mode of action studies of novel {2-(3-R-1H-1,2,4-triazol-5-yl)phenyl}amines to combat pathogenic fungi. Arch Pharm (Weinheim) (2019); [Epub ahead of print]. DOI: 10.1002/ardp.201900092.

Cairns T C,# Feurstein C,# Zheng X, Zheng P, Sun J, Meyer V. A quantitative image analysis pipeline for the characterization of filamentous fungal morphologies as a tool to uncover targets for morphology engineering: a case study using aplD in Aspergillus niger. Biotechnol Biofuels. (2019); 12:149. DOI:
10.1186/s13068-019-1473-0

Meyer V. Merging science and art through fungi. Fungal Biol Biotechnol. (2019); 6:5. DOI: 10.1186/s40694-019-0068-7

Cairns T C, Zheng X, Zheng P, Sun J, Meyer V. Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories. Biotechnol Biofuels (2019); 12:77. DOI: 10.1186/s13068-019-1400-4

Schmideder S, Barthel L, Friedrich T, Thalhammer M, Kovačević T, Niessen L, Meyer V, Briesen H. An X-ray microtomography-based method for detailed analysis of the three-dimensional morphology of fungal pellets. Biotechnol Bioeng. (2019); 1–11. DOI: 10.1002/bit.26956

Schäpe P, Kwon M J, Baumann B, Gutschmann B, Jung S, Lenz S, Nitsche B, Paege N, Schütze T, Cairns T C, Meyer V. Updating genome annotation for the microbial cell factory Aspergillus niger using gene co-expression networks. Nucleic Acids Research (2019); 47:2, 559–569; DOI: 10.1093/nar/gky1183

2018

Idnurm A, Meyer V. The CRISPR revolution in fungal biology and biotechnology, and beyond. Fungal Biol Biotechnol. (2018) 20;5:19. DOI: 10.1186/s40694-018-0064-3

Utesch T, de Miguel Catalina A, Schattenberg C, Paege N, Schmieder P, Krause E, Miao Y, McCammon A, Meyer V, Jung S, Mroginskia MA. A Computational Modeling Approach Predicts Interaction of the Antifungal Protein AFP from Aspergillus giganteus with Fungal Membranes via Its gamma-Core Motif. mSphere (2018); mSphere 3:e00377-18; DOI: 10.1128/mSphere.00377-18

Brandl J, Aguilar-Pontes M, Schäpe P, Noerregaard A, Arvas M, Ram AF, Meyer V, Tsang A, de Vries R, Andersen M. A community driven reconstruction of the Aspergillus niger metabolic network. Fungal Biology and Biotechnology (2018); 5:16; DOI: 10.1186/s40694-018-0060-7

Kurt T, Marbà‑Ardébol AM, Turan Z, Neubauer P, Junne S, Meyer V. Rocking Aspergillus:morphology-controlled cultivation of Aspergillus niger in a wave-mixed bioreactor for the production of secondary metabolites. Microb Cell Fact (2018) Aug 17:128, DOI: 10.1186/s12934-018-0975-y

Fiedler MRM, Barthel L., Kubisch C., Nai C., Meyer V. Construction of an improved Aspergillus niger platform for enhanced glucoamylase secretion. Microb Cell Fact (2018) Jun 17:95, DOI:10.1186/s12934-018-0941-8

Boecker S., Storm D., Meyer V., Richter L., Zobel S., Wanka F., Süssmuth R., Mühlenweg A. Method for obtaining nonribosomal peptides by heterologous expression of at least one nonribosomal peptide synthetase secondary in Aspergillus niger. Patent EP3119900B

Meyer V, Jung S. Antifungal Peptides of the AFP Family Revisited: Are These Cannibal Toxins?. Microorganisms (2018), 6(2), 50

Zheng X, Zheng P, Zhang K, Cairns T, Meyer V, Sun J, Ma Y. 5S rRNA promoter for guide RNA expression enabled highly efficient CRISPR/Cas9 genome editing in Aspergillus niger. ACS Synth. Biol (2018) Apr, DOI: 10.1021/acssynbio.7b00456

Cairns T, Nai C,  Meyer V. How a fungus shapes biotechnology: 100 years of Aspergillus niger research. Fungal Biology and Biotechnology (2018); 5:13; DOI: 10.1186/s40694-018-0054-5

Fiedler MRM, Cairns T, Koch O,  Kubisch C, Meyer V. Conditional expression of the small GTPase ArfA impacts secretion, morphology, growth, and actin ring position in Aspergillus niger. Front. Microbiol (2018), DOI: 10.3389/fmicb.2018.00878 Microbiolog

Boecker S, Grätz S, Kerwat D, Adam L, Schirmer D, Richter L, Schütze T, Petras D, Süssmuth RD, Meyer V. Aspergillus niger is a superior expression host for the production of bioactive fungal cyclodepsipeptides.  Fungal Biol Biotechnol. (2018) Mar 2;5:4

Nai C, Meyer V. From Axenic to Mixed Cultures: Technological Advances Accelerating a Paradigm Shift in Microbiology. Trends in Microbiology. 2018 Jun 26:6; klick here for Green OA

2017

Weinhold M, Mast‑Gerlach E, Meyer V. Vita activa in biotechnology: what we do with fungi and what fungi do with us. Fungal Biol Biotechnol  (2017) 4:14; DOI 10.1186/s40694-017-0041-2

Meyer V, Nai C and Idnurm A. Openness and visibility of fungal bio(techno)logy. Fungal Biol Biotechnol (2017) 4:9; DOI 10.1186/s40694-017-0038-x

Steiniger C, Hoffmann S, Mainz A,  Kaiser M,  Voigt K,  Meyer V and  Süssmuth R. Harnessing Fungal Nonribosomal Cyclodepsipeptide Synthetases for Mechanistic Insights and Tailored Engineering.  Chem. Sci. (2017) 8: 7834-7843; DOI:10.1039/C7SC03093B.

Idnurm A., Bailey AM, Cairns T, Elliott CE, Foster GD, Ianiriand G, Jeon J. A silver bullet in a golden age of functional genomics: the impact of Agrobacterium-mediated transformation of fungi. Fungal Biol Biotechnol (2017) 4:6; DOI 10.1186/s40694-017-0035-0

Schuetze T, Meyer V. Polycistronic gene expression in Aspergillus niger. Microb Cell Fact (2017), 16:162;  DOI 10.1186/s12934-017-0780-z

Nai C. Southern promises: a snapshot of the microbiology research landscape in South America based on bibliometric data. FEMS Microbiol Lett (2017) 364:16, DOI:10.1093/femsle/fnx162

Cairns T, Meyer V. In silico prediction and characterization of secondary metabolite biosynthetic gene clusters in the wheat pathogen Zymoseptoria tritici. BMC Genomics  (2017) 18:631; DOI:10.1186/s12864-017-3969-y

Yu Y, Hube B, Kämper J, Meyer V, Krappmann S. When Green and Red Mycology Meet: Impressions From an Interdisciplinary Forum on Virulence Mechanisms of Phyto- and Human-Pathogenic Fungi. Virulence (2017) 8:7; DOI:10.1080/21505594.2017.1356502

dos Reis TF, Nitsche BM, de Lima PBA, de Assis LJ, Mellano L, Meyer V, Corrêa dos Santos RA, Ries LNA, Goldman GH. The low affinity glucose transporter HxtB is also involved in glucose signalling and metabolism in Aspergillus nidulans. Sci Rep (2017) 7:45073; DOI: 10.1038/srep45073.

Fiedler MRM, Gensheimer T, Kubisch C, Meyer V. HisB as novel selection marker for gene targeting approaches in Aspergillus niger. BMC Microbiology (2017) 17:57; DOI: 10.1186/s12866-017-0960-3

de Vries et al. Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus. Genome Biology (2017) 18:28; DOI: 10.1186/s13059-017-1151-0

2016

Nai C, Meyer V. The beauty and the morbid: fungi as source of inspiration in contemporary art. Fungal Biology and Biotechnology 2016; 3:10 DOI: 10.1186/s40694-016-0028-4

Bignell E, Cairns T, Throckmorton K, Nierman W, Keller N. Secondary metabolite arsenal of an opportunistic pathogenic fungus.  Phil. Trans. R. Soc. B; DOI: 10.1098/rstb.2016.0023

Paege N, Jung S, Schäpe P, Müller-Hagen D, Ouedraogo JP, Heiderich C, Jedamzick J, Nitsche BM, van den Hondel CA, Ram AF, Meyer V. A Transcriptome Meta-Analysis Proposes Novel Biological Roles for the Antifungal Protein AnAFP in Aspergillus niger. PlosOne 2016; DOI:10.1371/journal.pone.0165755.s009

Meyer V, Idnurm A. The freedom of choice. Fungal Biology and Biotechnology 2016; 3:9 DOI: 10.1186/s40694-016-0027-5

Meyer V, Andersen M, Brakhage A, Braus G, Caddick M, Cairns T, de Vries R, Haarmann T, Hansen K, Hertz-Fowler C, Krappmann S, Mortensen U, Peñalva M, Ram AF, Head R. Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper. Fungal Biology and Biotechnology 2016; 3:6 DOI:10.1186/s40694-016-0024-8

Wanka F, Arentshorst M, Cairns T, Jørgensen T, Ram AF, Meyer V. Highly active promoters and native secretion signals for protein production during extremely low growth rates in Aspergillus niger.Microbial Cell Factories.2016, 15:145 DOI: 10.1186/s12934-016-0543-2

Nai C., Magrini B., Offe J. Let microorganisms do the talking, let us talk more about microorganisms. Fungal Biology and Biotechnology 2016;3:5 DOI 10.1186/s40694-016-0023-9

Park J, Hulsman M, Arentshorst M, Breeman M, Alazi E, Lagendijk EL, Rocha MC, Malavazi I, Nitsche BM, van den Hondel CA, Meyer V, Ram AF. Transcriptomic and molecular genetic analysis of the cell wall salvage response of Aspergillus niger to the absence of galactofuranose synthesis. Cell Microbiol. 2016 Jun; doi: 10.1111/cmi.12624

Meyer V, Nevoigt E, Wiemann P. The art of design. Fungal Genet Biol. 2016 Apr;89:1-2. doi:10.1016/j.fgb.2016.02.006

Wanka F,  Cairns T, Boecker S, Berens C, Happel A, Zheng X, Sun J,  Krappmann S ,  Meyer V. Tet-on, or Tet-off, that is the question: Advanced Conditional Gene Expression in Aspergillus. Fungal Genet Biol. 2016 Apr;89:72-83. doi:10.1016/j.fgb.2015.11.003

Boecker S, Zobel S, Meyer V, Süssmuth R. Rational biosynthetic approaches for the production of new-to-nature compounds in fungi. Fungal Genet Biol. 2016 Apr;89:89-101. doi:10.1016/j.fgb.2016.02.003

Zobel S,  Boecker S, Kulke D, Heimbach D, Meyer, Süssmuth RD. Reprogramming the biosynthesis of cyclodepsipeptide  synthetases rendering new to nature enniatins and beauvericins. Chembiochem. 2016 Feb;17(4):283-7. doi:10.1002/cbic.201500649

2015

Cairns TC, Studholme DJ, Talbot NJ, Haynes K. New and Improved Techniques for the Study of Pathogenic Fungi. Trends Microbiol. 2015 Nov 5. pii: S0966-842X(15)00226-7. doi: 10.1016/j.tim.2015.09.008.

Büttel Z, Díaz R, Dirnberger B, Flak M, Grijseels S, Kwon MJ, Nielsen JCF, Nygård Y et al. Unlocking the potential of fungi: the QuantFung project. Fungal Biology and Biotechnology 2015, 2:6

Van Munster JM, Nitsche BM, Akeroyd M, Dijkhuizen L, van der Maarel MJ, Ram AF. Systems approaches to predict the functions of glycoside hydrolases during the life cycle of Aspergillus niger using developmental mutants ∆brlA and ∆flbA. PLoS One 10(1):e0116269. doi:10.1371/journal.pone.0116269

Voshol GP,  Meyer V,  van den Hondel CAMJJ. GTP-binding protein Era: a novel gene target for biofuel production. BMC Microbiology 2015, 15:21. doi:10.1186/s12896-015-0132-1

Meyer V, Fiedler M, Nitsche B, King R. The Cell Factory Aspergillus Enters the Big Data Era: Opportunities and Challenges for Optimising Product Formation. Adv Biochem Eng Biotechnol 2015, 149:91-132. doi:10.1007/10_2014_297

2014

Boecker S., Storm D., Meyer V., Richter L., Zobel S., Wanka F., Süssmuth R., Mühlenweg A. Method for obtaining microbial secondary metabolites or derivatives thereof by heterologous expression of at least one synthetase of said secondary metabolites in filamentous fungi. Patent application WO2015140315 A2.

Fiedler MRM, Lorenz A, Nitsche BM, van den Hondel CAMJJ, Ram AFJ and Meyer V. The capacity of Aspergillus nigerto sense and respond to cell wall stress requires at least three transcription factors: RlmA, MsnA and CrzA. In: Fungal Biology and Biotechnology 2014 1:5 doi:10.1186/s40694-014-0005-8

Richter L, Wanka F, Boecker S, Storm D., Kurt T, Vural Ö, Süßmuth R and Meyer V. Engineering of Aspergillus niger for the production of secondary metabolites. In: Fungal Biology and Biotechnology 2014, 1:4  doi:10.1186/s40694-014-0004-9

Nitsche BM and Meyer V. Transcriptomics of Industrial Filamentous Fungi: A New View on Regulation, Physiology, and Application. In: Fungal Genomics, The Mycota XIII, 2nd Edition, M. Nowrousian (Ed.), Springer-Verlag Berlin Heidelberg 2014, pages 209-232.

Kwon MJ,  Arentshorst M, Fiedler M, de Groen FLM, Punt PJ, Meyer V, Ram AFJ. Molecular genetic analysis of vesicular transport in Aspergillus niger reveals partial conservation of the molecular mechanism of exocytosis in fungi. Microbiology(2014), 160,316–329, DOI10.1099/mic.0.074252-0

Martinez-Rojas E, Kurt T, Schmidt U, Meyer V and Garbe LA. A bifunctional enzyme from Rhodococcus erythropolis exhibiting secondary alcohol dehydrogenase-catalase activities (2014) Appl Microbiol Biotechnol 98(22):9249-58, doi: 10.1007/s00253-014-5808-2

2013

Meyer V. Morphologische Formfindung in Hyphenpilzen - gleich oder ungleich? Biospektrum 2013 May, DOI: 10.1007/s12268-013

Fiedler MRM,  Nitsche BM, Wanka F, Meyer V. Aspergillus: A Cell Factory with Unlimited Prospects. Applications of Microbial Engineering. CRC Press 2013. Pages 1-51

Kwon MJ, Nitsche BM, Arentshorst M,  Jørgensen TR, Ram AFJ, Meyer V. The transcriptomic signature of RacA activation and inactivation provides new insights into the morphogenetic network of Aspergillus niger. PLoS One 2013, 8(7):e68946.

Nitsche BM, Burggraaf-van Welzen AM, Lamers G, Meyer V, Ram AFJ. Autophagy promotes survival in aging submerged cultures of the filamentous fungusAspergillus niger. (2013) Appl Microbiol Biotechnol 97(18):8205-18. doi: 10.1007/s00253-013-4971-1

Krijgsheld P, Nitsche BM, Post H, Levin AM, Müller WH, Heck AJ, Ram AFJ, Altelaar AF, Wösten HA. Deletion of flbA Results in Increased Secretome Complexity and Reduced Secretion Heterogeneity in Colonies of Aspergillus niger (2013) J Proteome Res. 5;12(4):1808-19. doi: 10.1021/pr301154w

Schachtschabel D, Arentshorst M, Nitsche BM, Morris S, Nielsen KF, van den Hondel CA, Klis FM, Ram AFJ. The Transcriptional Repressor TupA in Aspergillus niger Is Involved in Controlling Gene Expression Related to Cell Wall Biosynthesis, Development, and Nitrogen Source Availability. PLoS One 2013, 8(10):e78102

Van Munster JM, Nitsche BM, Krijgsheld P, van Wijk A, Dijkhuizen L, Woesten HA, Ram AFJ, van der Maarel MJ. Chitinases CtcB and CfcI modifiy the cell wall in sporulating aerial mycelium of Aspergillus niger. Microbiology 2013, 159(Pt9):1853-67

Müller-Hagen D, Meyer V. David gegen Goliath-Entwicklung neuer antifungaler Wirkstoffe und Strategien (2013) labor&more

2012

Kwon MJ, Jørgensen TR, Nitsche BM, Arentshorst M, Park J, Ram AFJ, Meyer V. The transcriptomic fingerprint of glucoamylase over-expression in Aspergillus niger. BMC Genomics 2012, 13:701

Nitsche BM, Jørgensen TR, Akeroyd M, Meyer V, Ram AF. The carbon starvation response of Aspergillus niger during submerged cultivation: Insights from the transcriptome and secretome. BMC Genomics 2012 Aug 8;13(1):380

Nitsche BM, Ram AF, Meyer V. The use of open source bioinformatics tools to dissect transcriptomic data. Methods Mol Biol 2012, 835:311-31

Arentshorst M, Ram AF, Meyer V. Using non-homologous end-joining-deficient strains for functional gene analyses in filamentous fungi. Methods Mol Biol 2012, 835:133-50

2011

Nitsche BM, Crabtree J, Cerqueira GC, Meyer V, Ram AF, Wortman JR. New resources for functional analysis of omics data for the genus Aspergillus. In BMC Genomics. 2011 Oct 5;12(1):486

Binder U, Bencina M, Eigentler A, Meyer V, Marx F. The Aspergillus giganteus antifungal protein AFPNN5353 activates the cell wall integrity pathway and perturbs calcium homeostasis. In BMC Microbiol. 2011 Sep 23;11(1):209

Ouedraogo JP, Langendijk E, van den Hondel CAMJJ, Ram AFJ, Meyer V. Screening for compounds exerting antifungal activities. In Laboratory Protocols in Fungal Biology  (2011). Humana Press, New York.

Schmid J, Mueller-Hagen D, Sieber V, Meyer V. Nucleic and protein extraction methods for fungal exopolysaccharide producers. In Laboratory Protocols in Fungal Biology (2011). Humana Press, New York.

Schmid J, Meyer V, Sieber V. Scleroglucan: biosynthesis, production and application of a versatile hydrocolloid. Appl Microbiol Biotechnol 2011, 91:937-947

Meyer V, Wanka F, van Gent J, Arentshorst M, van den Hondel CA, Ram AF. Fungal Gene Expression on Demand: an Inducible, Tunable, and Metabolism-Independent Expression System for Aspergillus niger. Appl Environ Microbiol. 2011 May;77(9):2975-83

Ouedraogo JP, Hagen S, Spielvogel A, Engelhardt S, Meyer V. Survival Strategies of Yeast and Filamentous Fungi against the Antifungal Protein AFP. J Biol Chem. 2011 Apr 22;286(16):13859-68

Kwon MJ, Arentshorst M, Roos ED, van den Hondel CA, Meyer V, Ram AF. Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi. Mol Microbiol. 2011 Mar;79(5):1151-67

Meyer V, Wu B, Ram AF. Aspergillus as a multi-purpose cell factory: current status and perspectives. Biotechnol Lett. 2011 Mar;33(3):469-76

2010

Carvalho ND, Arentshorst M, Jin Kwon M, Meyer V, Ram AF. Expanding the ku70 toolbox for filamentous fungi: establishment of complementation vectors and recipient strains for advanced gene analyses. Appl Microbiol Biotechnol. 2010 Jul;87(4):1463-73

Schmid J, Müller-Hagen D, Bekel T, Funk L, Stahl U, Sieber V, Meyer V. Transcriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii. BMC Genomics. 2010 May 26;11:329

Meyer V, Minkwitz S, Schütze T, van den Hondel CA, Ram AF. The Aspergillus niger RmsA protein: A node in a genetic network? Commun Integr Biol. 2010 Mar;3(2):195-7.PMID: 20585521

Binder U, Oberparleiter C, Meyer V, Marx F. The antifungal protein PAF interferes with PKC/MPK and cAMP/PKA signalling of Aspergillus nidulans. Mol Microbiol. 2010 Jan;75(2):294-307

Meyer V, Ram AF, Punt PJ. Genetics, genetic manipulation and approaches to strain improvement of filamentous fungi (2010) Manual of Industrial Microbiology and Biotechnology. 3rd edition. Eds. Davies JE and Demain AL. New York, Wiley. pp 318-329

2009

Meyer V, Arentshorst M, Flitter SJ, Nitsche BM, Kwon MJ, Reynaga-Peña CG, Bartnicki-Garcia S, van den Hondel CA, Ram AF. Reconstruction of signaling networks regulating fungal morphogenesis by transcriptomics. Eukaryot Cell. 2009 Nov;8(11):1677-91

Wortman JR, Gilsenan JM, Joardar V, Deegan J, Clutterbuck J, Andersen MR, Archer D, Bencina M, Braus G, Coutinho P, von Döhren H, Doonan J, Driessen AJ, Durek P, Espeso E, Fekete E, Flipphi M, Estrada CG, Geysens S, Goldman G, de Groot PW, Hansen K, Harris SD, Heinekamp T, Helmstaedt K, Henrissat B, Hofmann G, Homan T, Horio T, Horiuchi H, James S, Jones M, Karaffa L, Karányi Z, Kato M, Keller N, Kelly DE, Kiel JA, Kim JM, van der Klei IJ, Klis FM, Kovalchuk A, Krasevec N, Kubicek CP, Liu B, Maccabe A, Meyer V, Mirabito P, Miskei M, Mos M, Mullins J, Nelson DR, Nielsen J, Oakley BR, Osmani SA, Pakula T, Paszewski A, Paulsen I, Pilsyk S, Pócsi I, Punt PJ, Ram AF, Ren Q, Robellet X, Robson G, Seiboth B, van Solingen P, Specht T, Sun J, Taheri-Talesh N, Takeshita N, Ussery D, vanKuyk PA, Visser H, van de Vondervoort PJ, de Vries RP, Walton J, Xiang X, Xiong Y, Zeng AP, Brandt BW, Cornell MJ, van den Hondel CA, Visser J, Oliver SG, Turner G. The 2008 update of the Aspergillus nidulans genome annotation: a community effort. Fungal Genet Biol. 2009 Mar;46 Suppl 1:S2-13

Harris SD, Turner G, Meyer V, Espeso EA, Specht T, Takeshita N, Helmstedt K. Morphology and development in Aspergillus nidulans: a complex puzzle. Fungal Genet Biol. 2009 Mar;46 Suppl 1:S82-S92

Schmid J, Stahl U, Meyer V. Genetic and metabolic engineering in filamentous fungi. 2009. In: Mycota XV, Physiology and Genetics. 1st edition. Eds. Anke T and Weber D. Springer-Verlag Berlin-Heidelberg. pp. 377-392

2008

Barakat H, Spielvogel A, Hassan M, El-Desouky A, El-Mansy H, Rath F, Meyer V, Stahl U. The antifungal protein AFP from Aspergillus giganteus prevents secondary growth of different Fusarium species on barley. Appl Microbiol Biotechnol. 2010 Jun;87(2):617-24.

Meyer V
. Genetic engineering of filamentous fungi--progress, obstacles and future trends. Biotechnol Adv. 2008 Mar-Apr;26(2):177-85

Meyer V. A small protein that fights fungi: AFP as a new promising antifungal agent of biotechnological value. Appl Microbiol Biotechnol. 2008 Feb;78(1):17-28

Meyer V, Arentshorst M, van den Hondel CA, Ram AF
. The polarisome component SpaA localises to hyphal tips of Aspergillus niger and is important for polar growth. Fungal Genet Biol. 2008 Feb;45(2):152-64

2007

Meyer V, Damveld RA, Arentshorst M, Stahl U, van den Hondel CA, Ram AF. Survival in the presence of antifungals: genome-wide expression profiling of Aspergillus niger in response to sublethal concentrations of caspofungin and fenpropimorph. J Biol Chem. 2007 Nov 9;282(45):32935-48

7) Hagen S, Marx F, Ram AF, Meyer V. The antifungal protein AFP from Aspergillus giganteus inhibits chitin synthesis in sensitive fungi. Appl Environ Microbiol. 2007 Apr;73(7):2128-34


Meyer V, Arentshorst M, El-Ghezal A, Drews AC, Kooistra R, van den Hondel CA, Ram AF. Highly efficient gene targeting in the Aspergillus niger kusA mutant. J Biotechnol. 2007 Mar 10;128(4):770-5.

2006

Szappanos H, Szigeti GP, Pál B, Rusznák Z, Szucs G, Rajnavölgyi E, Balla J, Balla G, Nagy E, Leiter E, Pócsi I, Hagen S, Meyer V, Csernoch L. The antifungal protein AFP secreted by Aspergillus giganteus does not cause detrimental effects on certain mammalian cells. Peptides. 2006 Jul;27(7):1717-25

Mueller D, Stahl U, Meyer V. Application of hammerhead ribozymes in filamentous fungi. J Microbiol Methods. 2006 Jun;65(3):585-95

2005

Meyer V, Spielvogel A, Funk L, Tilburn J, Arst HN Jr, Stahl U. Alkaline pH-induced up-regulation of the afp gene encoding the antifungal protein (AFP) of Aspergillus giganteus is not mediated by the transcription factor PacC: possible involvement of calcineurin. Mol Genet Genomics. 2005 Oct;274(3):295-306

Theis T, Marx F, Salvenmoser W, Stahl U, Meyer V. New insights into the target site and mode of action of the antifungal protein of Aspergillus giganteus. Res Microbiol. 2005 Jan-Feb;156(1):47-56

2003

Meyer V, Mueller D, Strowig T, Stahl U. Comparison of different transformation methods for Aspergillus giganteus. Curr Genet. 2003 Aug;43(5):371-7


Theis T, Wedde M, Meyer V, Stahl U. The antifungal protein from Aspergillus giganteus causes membrane permeabilization. Antimicrob Agents Chemother. 2003 Feb;47(2):588-93

2002

Meyer V, Stahl U. New insights in the regulation of the afp gene encoding the antifungal protein of Aspergillus giganteus. Curr Genet. 2002 Oct;42(1):36-42

Meyer V, Wedde M, Stahl U. Transcriptional regulation of the Antifungal Protein in Aspergillus giganteus. Mol Genet Genomics. 2002 Jan;266(5):747-57.

 

 

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